When you anticipate a big event, your brain sends the signals to your adrenal glands to produce a large amount of catecholamines, i.e. adrenaline, as well as the stress hormone, cortisol. So once your adrenal glands release cortisol, it will not only suppress the immune system, but will bind to the nerve cells that harbor the latent herpes virus and reactivate it. Adrenaline will also reactivate the virus by binding to another specific receptor on the nerve cells. The end result is a cold sore at the worst time (never fails)… This is a short-term stress response. The long-term stress, however, is a lot more complex, and inadvertently, derails the entire system, particularly metabolic, neurological, digestive, endocrine, and immune functions. Important to note that stress doesn’t have to be psychological, it can also be biological, such as blood sugar dysregulation or imbalanced gut microbiome (dysbiosis).

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